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About This Item
經驗公式（希爾表示法）:
C22H17N3O
CAS號碼:
分子量：:
339.39
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
推薦產品
品質等級
化驗
≥98% (HPLC)
形狀
powder
顏色
white to dark brown
溶解度
DMSO: ≥5 mg/mL
儲存溫度
2-8°C
SMILES 字串
O=C1N(CC2=CC=CC=C2)C(/C=C/C3=CN=CC=C3)=NC4=C1C=CC=C4
InChI
1S/C22H17N3O/c26-22-19-10-4-5-11-20(19)24-21(13-12-17-9-6-14-23-15-17)25(22)16-18-7-2-1-3-8-18/h1-15H,16H2/b13-12+
InChI 密鑰
GEKDQXSPTHHANP-OUKQBFOZSA-N
應用
RAD51 抑制剂B02已被用于：
- 测试其对猪卵母细胞极体排放（PBE）率的影响
- 用于猪胚胎的RAD51抑制
- 作为RAD51 抑制剂并用于测试其对诱导多能干细胞 (iPSC) 中靶向氨基酸替换 (TNS) 的影响
生化／生理作用
B02 (3-（苯甲基）-2-[（1E）-2-（3-吡啶基）乙烯基]-4（3H）-喹唑啉酮是一种吡啶基乙烯基喹唑啉酮化合物，可以穿透细胞。B02抑制人RAD51重组酶及之后核线的形成。它可以中止癌细胞中的同源重组（HR）修复活动。B02促进多发性骨髓瘤中的细胞凋亡，同时也是敏化多柔比星的关键。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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