SML0004

(S)-(+)-Clopidogrel hydrogensulfate

≥98% (HPLC)

• 同義詞: (S)-(+)-Clopidogrel bisulfate, (S)-(+)-Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate hydrogensulfate, Clopidogrel Bisulphate
• 經驗公式（希爾表示法）: C₁₆H₁₆ClNO₂S · H₂SO₄
• CAS號碼: 120202-66-6
• 分子量：: 419.90
• MDL號碼: MFCD00876395
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329825081
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 光學活性: [α]/D +54 to +70°, c = 0.5 in methanol
• 顏色: white to tan
• 溶解度: DMSO: ≥20 mg/mL (warmed)
• 起源: Bristol-Myers Squibb; Sanofi Aventis
• 儲存溫度: 2-8°C
• SMILES 字串: OS(O)(=O)=O.COC(=O)[C@@H](N1CCc2sccc2C1)c3ccccc3Cl
• InChI: 1S/C16H16ClNO2S.H2O4S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14;1-5(2,3)4/h2-5,7,9,15H,6,8,10H2,1H3;(H2,1,2,3,4)/t15-;/m0./s1
• InChI 密鑰: FDEODCTUSIWGLK-RSAXXLAASA-N
• 基因資訊: human ... P2RY12(64805)

描述

應用

(S)-(+)-Clopidogrel hydrogensulfate was used as standard in HPLC-MS/MS to detect clopidogrel and its thiol derivative in human plasma.

生化／生理作用

(S)-(+)-Clopidogrel hydrogen sulfate is an antithrombotic antiplatelet agent. It specifically and irreversibly inhibits the Purinoceptor P2Y12 subtype which inhibits ADP-induced platelet aggregation. (S)-(+)-Clopidogrel hydrogen sulfate is the active isomer.

特點和優勢

This compound is featured on the P2 Receptors: P2Y G-Protein Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Bristol-Myers Squibb and Sanofi Aventis. To browse the list of other pharma-developed compounds, Approved Drugs, and Drug Candidates, click here.

安全資訊

• 象形圖: GHS05,GHS09
• 訊號詞: Danger
• 危險聲明: H314,H411
• 防範說明: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• 危險分類: Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B
• 儲存類別代碼: 8A - Combustible corrosive hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable