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重要文件

SMB00605

Sigma-Aldrich

头孢匹林钠

同義詞:

头孢匹林钠 钠盐, 3-[(乙酰氧基)甲基]-8-氧代-7-{(4-吡啶巯基)乙酰基]氨基}-5-硫-1-氮杂双环[4.2.0]辛-2-烯-2-羧酸 单钠盐, 头孢吡硫钠

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About This Item

經驗公式(希爾表示法):
C17H16N3NaO6S2
CAS號碼:
分子量::
445.45
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:

形狀

powder

儲存條件

(Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)

抗生素活性譜

Gram-negative bacteria
Gram-positive bacteria

作用方式

cell wall synthesis | interferes

儲存溫度

2-8°C

SMILES 字串

[Na+].CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)CSc3ccncc3)C2=O)C([O-])=O

InChI

1S/C17H17N3O6S2.Na/c1-9(21)26-6-10-7-28-16-13(15(23)20(16)14(10)17(24)25)19-12(22)8-27-11-2-4-18-5-3-11;/h2-5,13,16H,6-8H2,1H3,(H,19,22)(H,24,25);/q;+1/p-1/t13-,16-;/m1./s1

InChI 密鑰

VGEOUKPOQQEQSX-OALZAMAHSA-M

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生化/生理作用

Cephapirin is a cephalosporin C antibiotic effective against Gram-positive and Gram-negative bacteria including Staphylococcus aureus, Escherichia coli, Klebsiella pneumonia and Proteus mirabilis.

包裝

25MG

準備報告

Cephapirin is soluble in H2O up to approximately 50 mg/mL and slightly soluble in DMSO and MeOH up to approximately 1 mg/mL.

其他說明

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

象形圖

Health hazardExclamation mark

訊號詞

Danger

危險分類

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Laboratory studies with a new cephalosporanic acid derivative.
D R Chisholm et al.
Antimicrobial agents and chemotherapy, 9, 244-246 (1969-01-01)
J Axelrod et al.
Applied microbiology, 22(5), 904-908 (1971-11-01)
Cephapirin, a new semisynthetic cephalosporin derivative, was found to have an antibacterial spectrum similar to that of cephalothin. Staphylococcus aureus was inhibited by cephapirin concentrations of 0.09 to 12.5 mug/ml. S. epidermidis, S. viridans, S. pyogenes, and Diplococcus pneumonia isolates
J L Bran et al.
Antimicrobial agents and chemotherapy, 1(1), 35-40 (1972-01-01)
Cephapirin sodium, a cephalosporin for parenteral use, was evaluated in vitro and in 27 patients. Cephapirin had activity equivalent to cephalothin against 25 strains each of Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, and Staphylococcus aureus; 10 strains each of Diplococcus

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