SMB00348

人参皂苷化合物 K

≥96% (HPLC)

• 同義詞: (3B,12B)-3,12-二羟基达马-24-烯-20-基 β-D-吡喃葡萄糖苷, 20 (S)-人参皂苷 Ck, 人参皂苷 K, 原人参二醇 20-O-葡萄糖苷
• 經驗公式（希爾表示法）: C₃₆H₆₂O₈
• CAS號碼: 39262-14-1
• 分子量：: 622.87
• 分類程式碼代碼: 12352205
• PubChem物質ID: 329824968
• NACRES: NA.25

屬性

• 化驗: ≥96% (HPLC)
• 形狀: powder
• 應用: metabolomics; vitamins, nutraceuticals, and natural products
• SMILES 字串: CC(C)=CCC[C@](C1C2[C@H](O)CC3[C@@]([C@]2(C)CC1)(C)CCC4C(C)(C)[C@@H](O)CC[C@@]43C)(C)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O
• InChI: 1S/C36H62O8/c1-20(2)10-9-14-36(8,44-31-30(42)29(41)28(40)23(19-37)43-31)21-11-16-35(7)27(21)22(38)18-25-33(5)15-13-26(39)32(3,4)24(33)12-17-34(25,35)6/h10,21-31,37-42H,9,11-19H2,1-8H3/t21?,22-,23-,24?,25?,26+,27?,28-,29+,30-,31+,33+,34-,35-,36+/m1/s1
• InChI 密鑰: FVIZARNDLVOMSU-KJULZEBLSA-N

描述

一般說明

人参皂苷化合物K是在人参根中发现的一种四环达玛烷型三萜皂苷。它是人参的主要成分，人参传统上用于增加对压力和衰老的抵抗力。

應用

• Combination of Electrochemistry and Mass Spectrometry to Study Nitric Oxide Metabolism and Its Modulation by Compound K in Breast Cancer Cells.: This research explores the interaction of Ginsenoside Compound K with nitric oxide metabolism in breast cancer cells, employing a combination of electrochemical techniques and mass spectrometry to elucidate the metabolic pathways and potential therapeutic effects of Compound K (Zhao et al., 2022).


• Metabolic analysis of Panax notoginseng saponins with gut microbiota-mediated biotransformation by HPLC-DAD-Q-TOF-MS/MS.: This article investigates the gut microbiota-mediated biotransformation of Panax notoginseng saponins, including Compound K, detailing the complex interactions and metabolic profiles in a biological system, which could inform their therapeutic use and bioavailability (Chen et al., 2018).

生化／生理作用

人参皂苷化合物K具有很多药理性质，包括抗糖尿病、抗炎、肝脏保护、抗过敏和抗癌作用。它在大鼠中也具有神经保护性质，可以从突触丧失和记忆损害中恢复。人参皂苷化合物K可以抑制人脐静脉内皮细胞（HUVEC）中多种基因表达，从而抑制内皮细胞的迁移和血管生成。

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302
• 防範說明: P264 - P270 - P301 + P312 - P501
• 危險分類: Acute Tox. 4 Oral
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable