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Key Documents

SCP0005

Sigma-Aldrich

MG-115 Peptide

≥95% (HPLC), lyophilized powder

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About This Item

經驗公式(希爾表示法):
C25H39N3O5
分子量::
461.59
分類程式碼代碼:
12352202
NACRES:
NA.32

product name

MG-115 / ASD 4955,

化驗

≥95% (HPLC)

形狀

lyophilized

成份

Peptide Content, ≥80%

儲存條件

protect from light

儲存溫度

−20°C

Amino Acid Sequence

Z-Leu-Leu-Nva-al

應用

MG-115 (Z-Leu-Leu-Nva-al) is used as a selective proteosome inhibitor.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Yolanda Pérez-Pertejo et al.
Parasitology, 138(9), 1082-1092 (2011-08-05)
Methionine adenosyltransferase (MAT) is an important enzyme for metabolic processes, to the extent that its product, S-adenosylmethionine (AdoMet), plays a key role in trans-methylation, trans-sulphuration and polyamine synthesis. Previous studies have shown that a MAT-overexpressing strain of Leishmania donovani controls
Estabelle Ang et al.
Journal of cellular physiology, 220(2), 450-459 (2009-04-15)
Proteasome inhibitors represent a promising therapy for the treatment of relapsed and/or refractory multiple myeloma, a disease that is concomitant with osteolysis and enhanced osteoclast formation. While blockade of the proteosome pathway has been recently shown to influence osteoclast formation
Karim Harhouri et al.
EMBO molecular medicine, 9(9), 1294-1313 (2017-07-05)
Hutchinson-Gilford progeria syndrome (HGPS) is a lethal premature and accelerated aging disease caused by a de novo point mutation in LMNA encoding A-type lamins. Progerin, a truncated and toxic prelamin A issued from aberrant splicing, accumulates in HGPS cells' nuclei

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