推薦產品
形狀
liquid
品質等級
比活性
(Antibacterial)
濃度
100 mg/mL in water
抗生素活性譜
Gram-negative bacteria
Gram-positive bacteria
mycobacteria
作用方式
protein synthesis | interferes
儲存溫度
−20°C
一般說明
Chemical structure: aminoglycoside
應用
Streptomycin is used to study mechanisms of streptomycin resistance and is often used together with penicillin and other agents to inhibit bacterial contamination in cell culture applications. It is recommended for use in molecular biology applications at 25-50 μg/mL, in cell culture applications at 100 mg/L and in embryo culture at 50 mg/L.
生化／生理作用
Mode of Action: Streptomycin acts by inhibiting prokaryote protein synthesis by binding to the S12 protein of the 30S ribosomal subunit, thus preventing the transition from imitation complex to chain-elongating ribosome. This causes miscoding or inhibits initiation.
Mode of Resistance: A mutation in rpsL, a gene for S12 ribosomal protein, prevents binding of streptomycin to the ribosome. An aminoglycoside phosphotransferase also inactivates streptomycin.
Antimicrobial spectrum: Streptomycin acts against gram-negative and gram-positive bacteria.
Mode of Resistance: A mutation in rpsL, a gene for S12 ribosomal protein, prevents binding of streptomycin to the ribosome. An aminoglycoside phosphotransferase also inactivates streptomycin.
Antimicrobial spectrum: Streptomycin acts against gram-negative and gram-positive bacteria.
儲存和穩定性
- Streptomycin ready made solution contains 100 mg/mL streptomycin sulfate in water.
- Streptomycin: sulfate salt ratio is 1:1.5.
- The product is packed under aseptic conditions.
訊號詞
Warning
危險聲明
危險分類
Repr. 2
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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Molecular medicine reports, 12(5), 6656-6662 (2015-09-02)
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