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Key Documents

SAB5702659

Sigma-Aldrich

Anti-MRPS15 Antibody, clone 8Q8T5, Rabbit Monoclonal

同義詞:

MRPS15, DC37, MPR-S15, RPMS15, S15mt, mitochondrial ribosomal protein S15

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.46

生物源

rabbit

品質等級

材料

colorless

無性繁殖

8Q8T5, monoclonal

形狀

liquid

分子量

28 kDa

物種活性

human

濃度

2.50 mg/mL

技術

immunofluorescence: 1:50 - 1:200
immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000

顏色

colorless

同型

IgG

免疫原序列

MSIDQRKKMLKNLRNTNYDVFEKICWGLGIEYTFPPLYYRRAHRRFVTKKALCIRVFQETQKLKKRRRALKAAAAAQKQAKRRNPDSPAKAIPKTLKDSQ

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... MRPS15(64960)

一般說明

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S15P family. The encoded protein is more than two times the size of its E. coli counterpart, with the 12S rRNA binding sites conserved. Between human and mouse, the encoded protein is the least conserved among small subunit ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 15q and 19q.

免疫原

A synthetic peptide corresponding to a sequence within amino acids 158-257 of human MRPS15 (P82914).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

應用

WB, IHC, IF/ICC

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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