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Merck
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Key Documents

SAB5702390

Sigma-Aldrich

Anti-Slit2 Antibody, clone 1T5A3, Rabbit Monoclonal

同義詞:

SLIL3, Slit-2

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.46

生物源

rabbit

品質等級

材料

colorless

無性繁殖

1T5A3, monoclonal

形狀

liquid

分子量

200 kDa

物種活性

rat, rat, human

濃度

1.90 mg/mL

技術

immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000

顏色

colorless

同型

IgG

免疫原序列

GHGGVLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCDREISCRGERIRDYYQKQQGYAACQTTKKVSRLECRGGCAGGQCCGPLRSKRR

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... SLIT2(9353)

一般說明

This gene encodes a member of the slit family of secreted glycoproteins, which are ligands for the Robo family of immunoglobulin receptors. Slit proteins play highly conserved roles in axon guidance and neuronal migration and may also have functions during other cell migration processes including leukocyte migration. Members of the slit family are characterized by an N-terminal signal peptide, four leucine-rich repeats, nine epidermal growth factor repeats, and a C-terminal cysteine knot. Proteolytic processing of this protein gives rise to an N-terminal fragment that contains the four leucine-rich repeats and five epidermal growth factor repeats and a C-terminal fragment that contains four epidermal growth factor repeats and the cysteine knot. Both full length and cleaved proteins are secreted extracellularly and can function in axon repulsion as well as other specific processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1400-1500 of human Slit2 (O94813).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

應用

WB, IHC

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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