SAB5702142

Anti-Proteinase 3/PR3 Antibody, clone 3I3M1, Rabbit Monoclonal

• 同義詞: ACPA, AGP7, C-ANCA, CANCA, MBN, MBT, NP-4, NP4, P29, PR-3, PR3
• 分類程式碼代碼: 12352203
• NACRES: NA.46

屬性

• 生物源: rabbit
• 品質等級: 100
• 材料: colorless
• 無性繁殖: 3I3M1, monoclonal
• 形狀: liquid
• 分子量: 28 kDa
• 物種活性: mouse, mouse
• 濃度: 0.39 mg/mL
• 技術: immunofluorescence: 1:50 - 1:200; western blot: 1:500 - 1:2000
• 顏色: colorless
• 同型: IgG
• 免疫原序列: MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHF
• UniProt登錄號: P24158
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... PRTN3(5657)

描述

一般說明

Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro. By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration. May play a role in neutrophil transendothelial migration, probably when associated with CD177.

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Proteinase 3/PR3 (P24158).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

應用

WB, IF/ICC

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1