SAB5700818

Anti-COL1A2 antibody produced in rabbit

• 同義詞: COL1A2, OI4
• 分類程式碼代碼: 12352203
• NACRES: NA.41
• 無性繁殖: polyclonal
• application: IHC; WB
• 物種活性: mouse, rat
• 技術: immunohistochemistry: 1:50-1:200; western blot: 1:500-1:2000

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: 129
• 物種活性: mouse, rat
• 濃度: 2.57 mg/ml
• 技術: immunohistochemistry: 1:50-1:200; western blot: 1:500-1:2000
• UniProt登錄號: P08123
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... COL1A2(1278)

描述

一般說明

This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

免疫原

A synthetic peptide corresponding to a sequence within amino acids 500-600 of human COL1A2 (NP_000080.2).

外觀

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

儲存和穩定性

Store at -20℃. Avoid freeze / thaw cycles.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable