SAB5700781

Anti-MRE11A antibody produced in rabbit

• 同義詞: ATLD, HNGS1, MRE11, MRE11A, MRE11B
• 分類程式碼代碼: 12352203
• NACRES: NA.41
• 無性繁殖: polyclonal
• application: IF; IP; WB
• 物種活性: mouse, human, rat
• 技術: immunofluorescence: 1:50-1:200; immunoprecipitation (IP): 1:50-1:100; western blot: 1:500-1:2000

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: 77; 80; 81
• 物種活性: mouse, human, rat
• 濃度: 2.82 mg/ml
• 技術: immunofluorescence: 1:50-1:200; immunoprecipitation (IP): 1:50-1:100; western blot: 1:500-1:2000
• UniProt登錄號: P49959
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... MRE11A(4361)

描述

一般說明

This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3′ to 5′ exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3′ to 5′ exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 1-205 of human MRE11A (NP_005581.2).

外觀

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

儲存和穩定性

Store at -20℃. Avoid freeze / thaw cycles.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable