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Merck
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Key Documents

SAB5700012

Sigma-Aldrich

Anti-CCND3 antibody produced in rabbit

同義詞:

CCND3, Cyclin D3, cyclin D3

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.43

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生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

22
24
32
9

物種活性

mouse, human

濃度

1.8 mg/ml

技術

western blot: 1:500-1:1000

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1 of 4

本產品
HPA000496SAB1411533AV35165
antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

antibody form

IgG fraction of antiserum

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

UniProt accession no.

P30281

UniProt accession no.

Q8WWL7

UniProt accession no.

Q8WWL7

UniProt accession no.

Q9UK17-2

species reactivity

mouse, human

species reactivity

human

species reactivity

human

species reactivity

rabbit, rat, guinea pig, human

mol wt

22, 32, 24, 9

mol wt

-

mol wt

antigen 12.2 kDa

mol wt

70 kDa

一般說明

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene.

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 201-292 of human CCND3 (NP_001751.1).

外觀

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

儲存和穩定性

Store at -20℃. Avoid freeze / thaw cycles.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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