SAB5500188

Anti-URI antibody, Rabbit monoclonal

recombinant, expressed in proprietary host, clone SP215, affinity isolated antibody

• 分類程式碼代碼: 12352203
• NACRES: NA.41
• 共軛: unconjugated
• application: FACS; IHC
• 無性繁殖: SP215, monoclonal
• 物種活性: human (tested)
• 技術: flow cytometry: 1:100; immunohistochemistry: 1:100

屬性

• 生物源: rabbit
• 品質等級: 100
• 重組細胞: expressed in proprietary host
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: SP215, monoclonal
• 物種活性: human (tested)
• 物種活性（以同源性預測）: bovine, mouse
• 技術: flow cytometry: 1:100; immunohistochemistry: 1:100
• 同型: IgG
• UniProt登錄號: O94763
• 運輸包裝: wet ice
• 儲存溫度: 2-8°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... URI1(8725)

描述

一般說明

Unconventional prefoldin RPB5 interactor (URI) is an oncogene required for the survival of some human carcinomas and is often amplified and over-expressed in subsets of carcinomas from ovary, breast, stomach, and lung. Activation of URI contributes an important mechanism for activating mitochondrial S6K1-BAD signaling and promoting cell survival through disabling PP1γ-dependent negative feedback inhibition. URI can negatively modulate RNA polymerase II subunit 5 (RPB5) and mediates resistance of cells to cisplatin.

免疫原

Synthetic peptide derived from the C-terminus of the human URI protein.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable