SAB4700394

Anti-Integrin beta 1 (CD29) Antibody

mouse monoclonal, MEM-101A

• 同義詞: Anti-ITGB1, Anti-Integrin β1 chain
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 產品名稱: Monoclonal Anti-CD29 antibody produced in mouse, clone MEM-101A, purified immunoglobulin, buffered aqueous solution
• 生物源: mouse
• 共軛: unconjugated
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: MEM-101A, monoclonal
• 形狀: buffered aqueous solution
• 物種活性: human, pig, canine
• 濃度: 1 mg/mL
• 技術: flow cytometry: suitable
• 同型: IgG1
• NCBI登錄號: NM_002211.3
• UniProt登錄號: P05556
• 運輸包裝: wet ice
• 儲存溫度: 2-8°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... ITGB1(3688)

描述

一般說明

Cluster of differentiation 29 (CD29), also known as integrin subunit β 1 (ITGB1), is a mechanosensor, encoded by the gene mapped to human chromosome 10p11.22. It is present in both normal cells and tumor-associated cells. The encoded protein has ubiquitous expression with a molecular mass of 130kDa.

The antibody MEM-101A reacts with CD29 (integrin beta1 chain), a 130 kDa single chain type I glycoprotein expressed as a heterodimer (non-covalently associated with the integrin alpha subunits 1-6). CD29 is broadly expressed on majority of hematopoietic and non-hematopoietic cells (leukocytes, platelets, fibroblasts, endothelial cells, epithelial cells and mast cells).

免疫原

Raji Burkitt′s lymphoma cell line

應用

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Flow cytometry/Cell sorting (1 paper)

生化／生理作用

Cluster of differentiation 29 (CD29) acts as an adhesive molecule in the development of de novo focal contact, keratinocyte migration and re-epithelialization of wound tissue. CD29 with/without CD27 induce apoptosis, in association with a multifunctional protein galectin (Gal)-3.

特點和優勢

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外觀

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable