SAB4700391

Monoclonal Anti-CD11c-APC antibody produced in mouse

clone BU15, purified immunoglobulin, buffered aqueous solution

• 同義詞: Anti-ITGAX
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: mouse
• 共軛: Allophycocyanin conjugate
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: BU15, monoclonal
• 形狀: buffered aqueous solution
• 物種活性: human, monkey, canine
• 技術: flow cytometry: suitable
• 同型: IgG1
• NCBI登錄號: NM_000887.3
• UniProt登錄號: P20702
• 運輸包裝: wet ice
• 儲存溫度: 2-8°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... ITGAX(3687)

描述

一般說明

Cluster of differentiation 11c (CD11c), also known as integrin subunit α X (ITGAX), is an antigen receptor, encoded by the gene mapped to human chromosome 16p11.2. The encode protein belongs to the adhesion molecule integrin family and is mainly expressed in natural killer cells, macrophages and even some activated B and T cells.

The antibody BU15 reacts with CD11c (alphaX, p150), a 150 kDa integrin expressed mainly on dendritic cells and tissue macrophages.

免疫原

Dendritic cells of synovial fluid

應用

The reagent is designed for Flow Cytometry analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 1e6 cells in a suspension. The content of a vial (1 mL) is sufficient for 100 tests.

生化／生理作用

Cluster of differentiation 11c (CD11c) delivers co-stimulatory signals to activated lymphocytes. Elevated expression of the gene decreased the risk of death and relapse in gastric cancer (GC) patients. The protein can be considered as an alternative prognosis marker for GC. Overexpression of CD11c in CD8⁺ cells might lead to the development of Behcet′s disease (BD).

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable