SAB4504720

抗 磷酸-p16-INK4a (pSer ¹⁵² ) 兔抗

affinity isolated antibody

• 同義詞: MTS1, Multiple tumor suppressor 1, p14ARF
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: rabbit
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: antigen 17 kDa
• 物種活性: human, rat, mouse
• 濃度: ~1 mg/mL
• 技術: ELISA: 1:1000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI登錄號: P42771
• UniProt登錄號: P42771
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: phosphorylation (pSer152)
• 基因資訊: human ... CDKN2A(1029)

描述

一般說明

p16INK4A (cyclin-dependent kinase inhibitor 2A isoform) and p14ARF (cyclin-dependent kinase inhibitor 2A) are encoded by the CDKN2A (cyclin-dependent kinase inhibitor 2A, multiple tumor suppressor) gene. p16INK4A is a low molecular weight protein. This gene is mapped to human chromosome 9p21.

免疫原

The antiserum was produced against synthesized peptide derived from human p16-INK4a around the phosphorylation site of Ser152.

Immunogen Range: 107-156

生化／生理作用

p16INK4A (cyclin-dependent kinase inhibitor 2A isoform) serves as a tumor suppressor and it negatively modulates cell growth by arresting cells in the G1 phase. Mutations in the CDKN2A (cyclin-dependent kinase inhibitor 2A, multiple tumor suppressor) gene is the main reason of inherited susceptibility to melanoma.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable