SAB4503993

Anti-phospho-Survivin (pThr³⁴) antibody produced in rabbit

affinity isolated antibody

• 分類程式碼代碼: 12352203
• NACRES: NA.41
• 共軛: unconjugated
• application: ELISA; WB
• 無性繁殖: polyclonal
• 物種活性: rat, human, mouse
• citations: 4
• 技術: ELISA: 1:1000; western blot: 1:500-1:1000

屬性

• 生物源: rabbit
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: antigen 16 kDa
• 物種活性: rat, human, mouse
• 濃度: ~1 mg/mL
• 技術: ELISA: 1:1000; western blot: 1:500-1:1000
• NCBI登錄號: O15392
• UniProt登錄號: O15392
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: phosphorylation (pThr34)
• 基因資訊: human ... BIRC5(332)

描述

一般說明

Survivin is also termed as BIRC5 (baculoviral inhibitor of apoptosis repeat-containing 5). It is a multifunctional protein. It belongs to the inhibitor of apoptosis protein (IAP) family. BIRC5 is expressed in fetal tissues and several human malignancies like melanoma. Survivin is located on human chromosome 17q25.

免疫原

The antiserum was produced against synthesized peptide derived from human Survivin around the phosphorylation site of Thr34.

Immunogen Range: 11-60

生化／生理作用

Survivin/BIRC5 (baculoviral inhibitor of apoptosis repeat-containing 5) plays a major role in ATL (adult T-cell leukemia/lymphoma) cell viability. It can block apoptosis and induce the multiplication of cell. BIRC5 also plays a major role in the development of cancer.

特點和優勢

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外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable