推薦產品
生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 58 kDa
物種活性
human, rat, mouse
濃度
~1 mg/mL
技術
ELISA: 1:10000
western blot: 1:500-1:1000
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... USP30(84749)
一般說明
Anti-USP30 Antibody detects endogenous levels of total USP30 protein.
USP30 (ubiquitin specific peptidase 30) is ubiquitin-specific deubiquitylase. It is located in the mitochondria. It is mapped to human chromosome 12q24.
免疫原
The antiserum was produced against synthesized peptide derived from human USP30.
Immunogen Range: 31-80
Immunogen Range: 31-80
應用
Anti-USP30, N-Terminal antibody has been used in western blotting.
生化/生理作用
USP30 controls atypical ubiquitin chains on mitochondria and PARK2 (parkinson juvenile disease protein 2) mediated mitophagy.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
nwg
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
Daily heat stress treatment rescues denervation-activated mitochondrial clearance and atrophy in skeletal muscle
The Journal of Physiology, 593(12), 2707-2720 (2015)
USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria
Nature Cell Biology, 17(2), 160-160 (2015)
Deubiquitinating enzymes regulate PARK2-mediated mitophagy
Autophagy, 11(4), 595-606 (2015)
A genome-wide study reveals rare CNVs exclusive to extreme phenotypes of Alzheimer disease
European Journal of Human Genetics, 20(6), 613-617 (2012)
Cell death discovery, 7(1), 211-211 (2021-08-13)
Deubiquitinates (DUBs) have been suggested as novel promising targets for cancer therapies. Accumulating experimental evidence suggests that some metal compounds have the potential to induce cancer cell death via inhibition of DUBs. We previously reported that auranofin, a gold(I)-containing agent
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