推薦產品
生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 53 kDa
物種活性
human
濃度
~1 mg/mL
技術
ELISA: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... SLC2A3(6515)
一般說明
Anti-GLUT3 Antibody detects endogenous levels of total GLUT3 protein.
Solute carrier family 2 member 3 (SLC2A3), also known as glucose transporter -3 (GLUT-3), is encoded by the gene mapped to human chromosome 12p13.3. The encoded protein belongs to the SLC2 family of GLUTs.
Solute carrier family 2 member 3 (SLC2A3), also known as glucose transporter -3 (GLUT-3), is encoded by the gene mapped to human chromosome 12p13.3. The encoded protein belongs to the SLC2 family of GLUTs.
免疫原
The antiserum was produced against synthesized peptide derived from human GLUT3.
Immunogen Range: 447-496
Immunogen Range: 447-496
應用
Anti-GLUT3, C-Terminal antibody produced in rabbit has been used in immunocytochemistry.
生化／生理作用
Solute carrier family 2 member 3 (SLC2A3)/ glucose transporter -3 (GLUT-3) along with GLUT1, facilitates the transport of dehydroascorbic acid (DHA). It also plays a vital role in cerebral glucose metabolism, providing energy for the activity of neurons, which, in turn, moderates the excitatory-inhibitory balance impacting both brain development and activity-dependent neural plasticity. SLC2A3 is essential for or optimal preimplantation embryo development and survival. Mutation in the gene increases the risk of susceptibility to attention-deficit/hyperactivity disorder (ADHD).
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
The facilitative glucose transporter GLUT3: 20 years of distinction.
Simpson I A, et al.
American Journal of Physiology. Endocrinology and Metabolism, 295(2), E242-E253 (2008)
Xiaogang Wu et al.
Neurosurgical review, 44(1), 411-422 (2020-01-04)
Hypoxia preconditioning (HPC), a well-established preconditioning model, has been shown to protect the brain against severe hypoxia or ischemia caused by traumatic brain injury (TBI), but the mechanism has not been well elucidated. Anaerobic glycolysis is the major way for
slc2a3 single?nucleotide polymorphism and duplication influence cognitive processing and population?specific risk for attention?deficit/hyperactivity disorder.
Merker S, et al.
Journal of Child Psychology and Psychiatry, and Allied Disciplines, 58(7), 798-809 (2017)
Energy requirements of odor transduction in the chemosensory cilia of olfactory sensory neurons rely on oxidative phosphorylation and glycolytic processing of extracellular glucose.
Villar P S, et al.
The Journal of Neuroscience, 37(23), 5736-5743 (2017)
The human Hox-bearing chromosome regions did arise by block or chromosome (or even genome) duplications.
Larhammar D, et al.
Genome Research, 12(12), 1910-1920 (2002)
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