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Merck
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重要文件

SAB4502482

Sigma-Aldrich

Anti-PTGER3 antibody produced in rabbit

affinity isolated antibody

同義詞:

EP3 subtype, PGE receptor, PGE2-R, Prostaglandin E2 receptor EP3 subtype, Prostanoid EP3 receptor

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41
共軛:
unconjugated
application:
ELISA
IF
無性繁殖:
polyclonal
物種活性:
human
citations:
4
技術:
ELISA: 1:10000
immunofluorescence: 1:100-1:500

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 43 kDa

物種活性

human

濃度

~1 mg/mL

技術

ELISA: 1:10000
immunofluorescence: 1:100-1:500

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... PTGER3(5733)

相關類別

一般說明

The PTGER3 (prostaglandin E receptor 3) gene is mapped to human chromosome 1p31.1 and encodes a Gαi coupled receptor protein. It is predominantly localized to the brain in the neurons and activated glial cells. Anti-PTGER3 antibody detects endogenous levels of total PTGER3 protein.

免疫原

The antiserum was produced against synthesized peptide derived from human PTGER3.

Immunogen Range: 16-65

生化/生理作用

Prostaglandin E receptor 3 (PTGER3) serves as a receptor for prostaglandin (PG) E1 and E2, to carry out a number of physiological processes. PTGER3 specifically functions to reduce adenylyl cyclase action. It is involved in the activation of the Ras signaling pathway.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

Lot/Batch Number

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存取文件庫

Inhibition of prostaglandin E2 receptor EP3 mitigates thrombin-induced brain injury
Han, X, et al.
Journal of Cerebral Blood Flow and Metabolism, 36(6), 1059-1074 (2016)
The key residue within the second extracellular loop of human EP3 involved in selectively turning down PGE 2-and retaining PGE 1-mediated signaling in live cells
Akasaka H
Archives of Biochemistry and Biophysics, 616, 20-29 (2017)
Tuberin Regulates Prostaglandin Receptor-Mediated Viability, via Rheb, in mTORC1-Hyperactive Cells
Li C, et al.
Molecular Cancer Research (2017)
Loss of heterozygosity at chromosome 1p in different solid human tumours: association with survival.
Ragnarsson G
British Journal of Cancer, 79(9-10), 1468-1474 (1999)

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