SAB4502149

Anti-PDGF Receptor β antibody produced in rabbit

affinity isolated antibody

• 同義詞: CD140b, PDGF-R-β, PDGFR, PDGFR-β, kinase PDGFR-β
• MDL號碼: MFCD00164777
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: rabbit
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: antigen 123 kDa
• 物種活性: rat, mouse, human
• 濃度: ~1 mg/mL
• 技術: ELISA: 1:40000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI登錄號: P09619
• UniProt登錄號: P09619
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... PDGFRB(5159)

描述

一般說明

The PDGFRB (platelet-derived growth factor receptor β) gene is mapped to human chromosome 5q32. The encoded protein is a cell surface tyrosine kinase receptor. Anti-PDGF receptor β antibody detects endogenous levels of total PDGF receptor β protein.

免疫原

The antiserum was produced against synthesized peptide derived from human PDGF Receptor beta.

Immunogen Range: 718-767

生化／生理作用

PDGFRB (platelet-derived growth factor β) has its key role in cell proliferation, differentiation and survival. It also mediates cell movement and tissue repair mechanism. PDGFβ functions as a mitogen, by binding to the PDGF receptor β. Variation in PDGFRB gene leads to a number of cancer types including glioblastoma, dermatofibrosarcoma, medulloblastoma and endocrine pancreatic tumor. PDGFR-β signaling pathway, can thus serve as an important target for cancer therapy.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: nwg
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable