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重要文件

SAB4500430

Sigma-Aldrich

Anti-CPB2 antibody produced in rabbit

affinity isolated antibody

同義詞:

CBPB2, CPU, carboxypeptidase B2, carboxypeptidase U, plasma carboxypeptidase B

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41
無性繁殖:
polyclonal
application:
ELISA
WB
物種活性:
human
技術:
ELISA: 1:40000
western blot: 1:500-1:1000
citations:
2

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 48 kDa

物種活性

human

濃度

~1 mg/mL

技術

ELISA: 1:40000
western blot: 1:500-1:1000

NCBI登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... CBPB2(1361)

一般說明

Anti-CPB2 Antibody detects endogenous levels of total CPB2 protein.

免疫原

The antiserum was produced against synthesized peptide derived from human CPB2.

Immunogen Range: 321-370

應用

Anti-CPB2, C-Terminal antibody produced in rabbit is suitable for indirect ELISA and western blot analysis.

生化/生理作用

CPB2 exhibit antifibrinolytic property. It cleaves the C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins to regulate their activities. By the carboxypeptidase activity, CPB2 release C-terminal Lys and Arg residues from partially degraded fibrin which finally indicates towards an antifibrinolytic effect.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

Lot/Batch Number

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D L Eaton et al.
The Journal of biological chemistry, 266(32), 21833-21838 (1991-11-15)
A novel plasminogen-binding protein has been isolated from human plasma utilizing plasminogen-Sepharose affinity chromatography. This protein copurified with alpha 2 antiplasmin when the plasminogen affinity column was eluted with high concentrations of epsilon-aminocaproic acid (greater than 20 mM). Analysis by
S S Mao et al.
The Journal of biological chemistry, 274(49), 35046-35052 (1999-11-27)
Plasma carboxypeptidase B (PCB) is an exopeptidase that exerts an antifibrinolytic effect by releasing C-terminal Lys and Arg residues from partially degraded fibrin. PCB is produced in plasma via limited proteolysis of the zymogen, pro-PCB. In this report, we show

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