生物源
rabbit
品質等級
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous glycerol solution
物種活性
human
技術
immunohistochemistry: 1: 100-300
登錄號
NP_002984
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... CXCL6(6372)
一般說明
CXCL6 (C-X-C motif chemokine ligand 6)/GCP-2 (granulocyte chemotactic protein-2), a pro-inflammatory neutrophil chemoattractant, is mapped to human chromosome 4q12-q13. It belongs to the ELR+ CXC family. It is synthesized by mesenchymal cells like fibroblasts and micro and macrovascular endothelial cells.
免疫原
Synthetic peptide of human CXCL6
生化／生理作用
CXCL6 (C-X-C motif chemokine ligand 6)/GCP-2 (granulocyte chemotactic protein-2) plays an important role in the recruitment and activation of neutrophils. It acts as an autocrine growth factor resulting in tumor progression and metastasis. CXCL6 participates in menstruation, implantation and the maintenance of early pregnancy. GCP-2 plays an important role in mucosal chronic inflammatory conditions like inflammatory bowel disease or chronic rhinosinusitis.
特點和優勢
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外觀
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Pooja Mittal et al.
American journal of reproductive immunology (New York, N.Y. : 1989), 60(3), 246-257 (2008-09-11)
CXCL6 is a potent pro-inflammatory neutrophil chemoattractant and activator whose activity during pregnancy is not well-established. The purpose of this study was to determine if CXCL6 is present in amniotic fluid (AF) and if CXCL6 concentrations in AF change with
M Kebschull et al.
Journal of periodontal research, 44(4), 465-471 (2008-10-10)
Mucosal inflammatory responses are orchestrated largely by pro-inflammatory chemokines. The chemokine granulocyte chemotactic protein 2 (CXCL6) is involved in neutrophil recruitment and migration. Previous studies have shown that granulocyte chemotactic protein 2 is up-regulated during mucosal inflammation (e.g. in inflammatory
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