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Merck
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重要文件

SAB4300599

Sigma-Aldrich

Anti-MET (Ab-1003) antibody produced in rabbit

affinity isolated antibody

同義詞:

Anti-AUTS9 antibody produced in rabbit, Anti-HGFR antibody produced in rabbit, Anti-RCCP2 antibody produced in rabbit, Anti-c-Met antibody produced in rabbit, Anti-met proto-oncogene (hepatocyte growth factor receptor) antibody produced in rabbit

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

~156 kDa

物種活性

rat, human, mouse

濃度

1 mg/mL

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
western blot: 1:500-1:1000

同型

IgG

免疫原序列

(V-D-Y-R-A)

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... MET(4233)

一般說明

MET/c-Met (mesenchymal-epithelial transition factor) is a tyrosine kinase receptor , that is located on chromosome 7q31.

免疫原

Peptide sequence around aa. 1001-1005 (V-D-Y-R-A), according to the protein MET.

生化/生理作用

MET/c-Met (mesenchymal-epithelial transition factor) controls several biological processes like cell scattering, survival, proliferation, migration and c-MET signaling.(31)

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

標靶描述

Receptor for hepatocyte growth factor and scatter factor. Has a tyrosine-protein kinase activity. Functions in cell proliferation, scattering, morphogenesis and survival.

外觀

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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存取文件庫

The c-Met receptor: Implication for targeted therapies in colorectal cancer
Safaie Qamsari E, et al.
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine, 39(5) (2017)
Nayeon Lee et al.
Biochemistry and biophysics reports, 26, 100973-100973 (2021-03-16)
Hepatocyte growth factor (HGF) is a neurotrophic factor and its role in peripheral nerves has been relatively unknown. In this study, biological functions of HGF and its receptor c-met have been investigated in the context of regeneration of damaged peripheral
Kyeong Ryang Ko et al.
Scientific reports, 8(1), 8316-8316 (2018-05-31)
During the peripheral nerve regeneration process, a variety of neurotrophic factors play roles in nerve repair by acting on neuronal or non-neuronal cells. In this report, we investigated the role(s) of hepatocyte growth factor (HGF) and its receptor, c-met, in
Phase II study of the c-MET inhibitor tivantinib (ARQ 197) in patients with relapsed or relapsed/refractory multiple myeloma
Baljevic M, et al.
Annals of Hematology, 96(6), 977-985 (2017)
Phase II and biomarker study of the dual MET/VEGFR2 inhibitor foretinib in patients with papillary renal cell carcinoma
Choueiri TK, et al.
Journal of Clinical Oncology, 31(2), 181-186 (2013)

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