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重要文件

SAB4300526

Sigma-Aldrich

Anti-ITGB3 (Ab-785) antibody produced in rabbit

affinity isolated antibody

同義詞:

Anti-CD61 antibody produced in rabbit, Anti-GP3A antibody produced in rabbit, Anti-GPIIIa antibody produced in rabbit, Anti-integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) antibody produced in rabbit

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

~110 kDa

物種活性

human, mouse

濃度

1 mg/mL

技術

western blot: 1:500-1:1000

同型

IgG

免疫原序列

(I-T-Y-R-G)

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... ITGB3(3690)

免疫原

Peptide sequence around aa. 783-787 (I-T-Y-R-G), according to the protein ITGB3.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

標靶描述

The Itg-Beta3 gene encodes the beta subunit of the platelet membrane adhesive protein receptor complex Itg-Beta3 protein, which belongs to the Integrin class of cell adhesion molecule receptors that share a common heterotrimeric structure with Alpha and Beta subunits. It is a common Beta subunit of the platelet complex and of two other Integrins (Fibronectin and Vitronectin Receptors), which have distinct Alpha subunits. Itg-Beta3 has been implicated in a wide variety of functions, including platelet aggregation and thrombosis and implantation, placentation, angiogenesis, bone remodeling, and tumor progression. Glanzmann Thrombasthenia can result from defects in the genes for either the Itg-Alpha2B or the Itg-Beta3 subunit.

外觀

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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S Badrnya et al.
Thrombosis and haemostasis, 112(1), 128-136 (2014-02-28)
Circulating plasma microvesicles (PMVs) and their microRNA content are involved in the development of atherosclerosis and could serve as biomarkers for cardiovascular disease (CVD) progression. However, little is known on how smoking influences the levels of PMVs and microRNA signatures

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