SAB4300086

Anti-phospho-MAPT (pThr¹⁸¹) antibody produced in rabbit

affinity isolated antibody

• 同義詞: Anti-DDPAC antibody produced in rabbit, Anti-FLJ31424 antibody produced in rabbit, Anti-FTDP-17 antibody produced in rabbit, Anti-MAPTL antibody produced in rabbit, Anti-microtubule-associated protein tau antibody produced in rabbit
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: rabbit
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: ~48 kDa; ~62 kDa; ~78 kDa
• 物種活性: rat, mouse, human
• 濃度: 1 mg/mL
• 技術: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; western blot: 1:500-1:1000
• 同型: IgG
• 免疫原序列: (P-K-TP-P-P)
• NCBI登錄號: NP_001116538.1
• UniProt登錄號: P10636
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: phosphorylation (pThr181)
• 基因資訊: human ... MAPT(4137)

描述

免疫原

Peptide sequence around phosphorylation site of threonine 181 (P-K-T(p)-P-P), according to the protein MAPT.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

標靶描述

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

外觀

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable