SAB4200651

Monoclonal Anti-Histone H3 (C-terminal) antibody produced in mouse

clone H6.10, purified from hybridoma cell culture

• 分類程式碼代碼: 12352203
• NACRES: NA.41
• 無性繁殖: H6.10, monoclonal
• application: IF
• 物種活性: chicken, human, monkey, hamster, canine
• 技術: immunoblotting: 0.25-0.5 μg/mL using using histones isolated from human HeLa cells.; immunofluorescence: 5-10 μg/mL using using HeLa cells.
• citations: 9

屬性

• 生物源: mouse
• 品質等級: 200
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: H6.10, monoclonal
• 形狀: buffered aqueous solution
• 分子量: antigen ~14 kDa
• 物種活性: chicken, human, monkey, hamster, canine
• 濃度: ~1 mg/mL
• 技術: immunoblotting: 0.25-0.5 μg/mL using using histones isolated from human HeLa cells.; immunofluorescence: 5-10 μg/mL using using HeLa cells.
• 同型: IgG1
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... HIST1H3A(8350)

描述

一般說明

Histone cluster 1 H3A (HIST1H3A) belongs to the H3 histone family. The gene encoding it is localized on human chromosome 6.

Monoclonal Anti-Histone H3 (C-terminal) (mouse IgG1 isotype) is derived from the hybridoma H6.10 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a synthetic peptide corresponding to a sequence at the C terminal region of human Histone H3, conjugated to KLH.

免疫原

a synthetic peptide corresponding to a sequence at the C terminal region of human Histone H3.

應用

Monoclonal Anti-Histone H3 (C-terminal) antibody has been used in

• immunoblotting
• immunofluorescence
• western blotting

生化／生理作用

H3.1 (Histone 3-variant 1) is involved in gene silencing as well as gene activation. Histones H3 and H4 are the predominant histones subjected to extensive covalent modifications. Mutations in histone H3 were identified in various tumors.

Histone cluster 1 H3A (HIST1H3A) has been associated with DNA replication.

外觀

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable