SAB4200617

Monoclonal Anti-Myb antibody from mouse

clone MB-8, purified immunoglobulin

• 同義詞: Proto-oncogene c-Myb, Transcriptional activator Myb, Transcriptional activator Myb; Proto-oncogene c-Myb
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: mouse
• 品質等級: 200
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: MB-8, monoclonal
• 物種活性: human, mouse
• 濃度: ~1 mg/mL
• 技術: flow cytometry: 2.5-5 μg/test using using HL-60 cells.; immunoblotting: 0.5-1 μg/mL using using Jurkat total cell extract.; immunofluorescence: 2-4 μg/mL using using HeLa cells.
• 同型: IgG1
• UniProt登錄號: P10242
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... MYB(4602)

描述

一般說明

Monoclonal Anti-Myb (mouse IgG1 isotype) is derived from the hybridoma MB-8 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice. MYB proto-oncogene, transcription factor is encoded by the gene mapped to human chromosome 6q23.3.

特異性

Monoclonal Anti-Myb recognizes human and mouse Myb.

免疫原

synthetic peptide corresponding to a sequence at the N-terminal region of human Myb.

應用

Monoclonal Anti-Myb antibody from mouse may be used in:

• immunoblotting
• flow cytometry
• immunocytochemistry

生化／生理作用

MYB is a transcription factor that regulates stem and progenitor cells in the bone marrow, colonic crypts and a neurogenic region of the adult brain. Loss of MYB activity in these cells leads to severe or lethal phenotypes. MYB is an oncogene and is observed in some human leukemias. In addition, It is also observed that MYB is activated in colon and breast cancer.

外觀

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

儲存和穩定性

For extended storage, freeze at -20 ˚C in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable