SAB4200451

Anti-NMD3 antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

• 同義詞: Anti-60S Ribosomal export protein NMD3, Anti-CGI-07, Anti-NMD3 homolog (S. cerevisiae)
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 200
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: antigen ~58 kDa
• 物種活性: human, rat, mouse
• 濃度: ~1.0 mg/mL
• 技術: indirect immunofluorescence: 2.5-5 μg/mL using human HeLa cells.; western blot: 2.5-5.0 μg/mL using whole extracts of HEK-293T cells over-expressing mouse NMD3.
• UniProt登錄號: Q96D46
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... NMD3(51068) ; mouse ... Nmd3(97112) ; rat ... Nmd3(310512)

描述

一般說明

NMD3 ribosome export adaptor (NMD3) is an adaptor for 60S subunit export via the export receptor CRM1 (XPO1). In human, the C-terminal domain of NMD3 comprises a CRM1- dependent leucine-rich nuclear export signal (NES) and a nuclear localization signal (NLS) in its. Two zinc-binding centres and the ribosome-binding domain forms the N-terminal domain.

免疫原

peptide corresponding to an internal region of human NMD3, conjugated to KLH. The corresponding sequence is identical in mouse, rat, monkey, bovine and dog.

應用

Anti-NMD3 antibody produced in rabbit has been used in immunoblotting and immunofluorescence.

生化／生理作用

NMD3 ribosome export adaptor (NMD3) is a highly conserved nucleocytoplasmic shuttling protein, essential for nuclear export of 60S ribosomal subunits.

外觀

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable