SAB3700555

Anti-Rat IgG (Fc specific), F(ab′)₂ fragment, highly cross adsorbed-Peroxidase antibody produced in goat

affinity isolated antibody, lyophilized powder

• 同義詞: HRP
• 分類程式碼代碼: 12352203
• NACRES: NA.46

屬性

• 生物源: goat
• 品質等級: 100
• 共軛: peroxidase conjugate
• 抗體表格: affinity isolated antibody
• 抗體產品種類: secondary antibodies
• 無性繁殖: polyclonal
• 形狀: lyophilized powder
• 物種活性: rat
• 技術: immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• 運輸包裝: wet ice
• 儲存溫度: 2-8°C
• 目標翻譯後修改: unmodified

描述

一般說明

Immunoglobulin G (IgG) is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4 with different heavy chains, named γ1, γ2, γ3, and γ4, respectively. Limited digestion using papain cleaves the antibody into three fragments, two of which are identical and contain the antigen-binding activity. They are known as Fragment antigen binding (Fab) fragments. These fragments contain the light chains paired with the VH and CH1 domains of the heavy chains. The third fragment does not possess antigen-binding activity and is known as fragment crystallizable (Fc). It interacts with cells and effector molecules. The Fc fragment contains the CH2 and CH3 domains of the antibody molecule. Maternal IgG is the only antibody transported across the placenta to the fetus. It passively immunizes the infants.

特異性

This product was prepared from monospecific antiserum by immunoaffinity chromatography using Rat IgG coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities, pepsin digestion and chromatographic separation. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Peroxidase, Anti-Goat Serum, Rat IgG, Rat IgG F(c) and Rat Serum. No reaction was observed against Anti-Pepsin, Anti-Goat IgG F(c), Rat IgG F(ab′)2 or Bovine, Horse, Human Serum Proteins.

免疫原

Rat IgG F(c) fragment

物理性質

Antibody format: IgG F(ab′)2

外觀

Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free

重構

Reconstitute with 500 μ;L deionized water (or equivalent).

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H317
• 防範說明: P280
• 危險分類: Skin Sens. 1
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable