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Merck
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Key Documents

SAB3501209

Sigma-Aldrich

Anti-West Nile Virus Core antibody produced in rabbit

affinity isolated antibody

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About This Item

分類程式碼代碼:
12352203

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

liquid

物種活性

West Nile virus

濃度

1 mg/mL

技術

ELISA: suitable
immunofluorescence: suitable
western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

一般說明

West Nile Virus Core Antibody: West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins which play a major role for WNV entry into target cells. The viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway as delivery of core gene delivery into the striatum of mouse brain and skeletal muscle resulted in cell death and inflammation.

免疫原

West Nile Virus Core antibody was raised against a synthetic peptide corresponding to 15 amino acids near the carboxy terminus of the West Nile Virus core protein.The immunogen is located within amino acids 80 - 130 of West Nile Virus Core.

應用

West Nile virus Core antibody can be used for the detection of the WNV Core protein in ELISA. It will detect 10 ng of free peptide at 1 μg/mL. This antibody will also detect the protein in immunoblot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 20 μg/mL. Antibody validated: Western Blot in human samples and Immunocytochemistry in monkey samples. All other applications and species not yet tested.

外觀

Supplied in PBS containing 0.02% sodium azide.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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