推薦產品
生物源
mouse
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
GT1315, monoclonal
形狀
buffered aqueous solution
分子量
189kDa
物種活性
human
濃度
1mg/mL
技術
western blot: 1:500-1:3000
同型
IgG1
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... CEP152(22995)
一般說明
CEP152 (centrosomal protein 152), a mammalian ortholog of Drosphila asterless is a component of mammalian centrosomes. It is located on human chromosome 15.
免疫原
Recombinant protein encompassing a sequence within the N-terminus region of human CEP152.
應用
Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
生化/生理作用
This gene encodes a protein that is thought to be involved with centrosome function. Mutations in this gene have been associated with primary microcephaly (MCPH4). Alternative splicing results in multiple transcript variants. [provided by RefSeq]
CEP152 (centrosomal protein 152) plays an important role in cell division and development. It is highly essential for the recruitment of centriole of Plk4 (polo-like kinase 4) and centriole duplication at the time of cell cycle.
CEP152 (centrosomal protein 152) plays an important role in cell division and development. It is highly essential for the recruitment of centriole of Plk4 (polo-like kinase 4) and centriole duplication at the time of cell cycle.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
其他說明
Purification: Affinity purified by Protein G
外觀
Phosphate-buffered saline, no preservative added.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
Human Cep192 and Cep152 cooperate in Plk4 recruitment and centriole duplication.
Journal of Cell Science, 126(14), 3223-3233 (2013)
Primary autosomal recessive microcephaly: homozygosity mapping of MCPH4 to chromosome 15.
American Journal of Human Genetics, 65(5), 1465?1469-1465?1469 (1999)
Mutations in centrosomal protein CEP152 in primary microcephaly families linked to MCPH4.
American Journal of Human Genetics, 87(1), 40-51 (2010)
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