SAB2501761

Anti-ZNF703 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• 同義詞: FLJ14299, ZNF503L, hypothetical protein LOC80139, zinc finger protein 703
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: goat
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 物種活性: pig, canine, human
• 技術: indirect ELISA: suitable; western blot: suitable
• UniProt登錄號: Q9H7S9
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... ZNF703(80139)

描述

一般說明

ZNF703 (zinc finger protein 703) belongs to the NET (Noc/Nlz, Elbow, and Tlp-1) protein family, and the corresponding gene is localized to human chromosome 8p12.

免疫原

Peptide with sequence C-ELDKKDQEPKPSPE, from the internal region of the protein sequence according toNP_079345.1

生化／生理作用

ZNF703 (zinc finger protein 703) is a frequently modified gene in the pan-cancer group. In zebrafish and Drosophila, it plays an essential role in embryonic development. Amplification of this gene leads to loss of cell-cell adhesion, and thus, an increase in proliferation and migration. In patients with head and neck squamous cell carcinomas (HNSCC), the overexpression of this protein is linked with poor overall survival. It functions as an oncogene in luminal B breast cancer and gastric cancer, and in colorectal cancer (CRC) it facilitates tumor proliferation and invasion. In CRC patients, it is linked with poor prognosis.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable