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Key Documents

SAB2501424

Sigma-Aldrich

Anti-IGF1 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

同義詞:

Anti-IGF1A, Anti-IGFI, Anti-OTTHUMP00000195084, Insulin-like growth factor 1, Insulin-like growth factor 1 (somatomedin C)

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

goat

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

human

技術

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... IGF1(3479)

一般說明

Insulin-like growth factor 1 (IGF1) is a single polypeptide chain protein with three disulfide bridges. It is mainly produced by the liver and a wide range of extra-hepatic tissues. IGF1 is seen in normal and neoplastic breasts. The IGF1 gene is 84779 bp long and is made of 6 different exons. IGF-1 gene is located on human chromosome 12q23.2.

免疫原

Peptide with sequence RSVRAQRHTD, from the internal region of the protein sequence according to NP_001104753.1; NP_001104754.1; NP_001104755.1; NP_000609.1

應用

Anti-IGF1 antibody produced in goat has been used in western blotting.

生化/生理作用

Insulin-like growth factor 1 (IGF1) protein is essential for the development of children and adults. It plays a crucial role in general anabolic processes. IGF1 participates in differentiation and cell proliferation. It plays a key role in osteogenesis, muscle repair, and hypertrophy after trauma. IGF1 is also involved in the generation of axons in nerves and regeneration of a nerve after ischemic insult. It is known to participate in the clinical sequelae of Laron′s dwarfism. IGF1 is required for normal breast development.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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存取文件庫

M Ouni et al.
The pharmacogenomics journal, 16(1), 102-106 (2015-04-15)
Short children using growth hormone (GH) to accelerate their growth respond to this treatment with a variable efficacy. The causes of this individual variability are multifactorial and could involve epigenetics. Quantifying the impact of epigenetic variation on response to treatments
T L Wise
Genes, brain, and behavior, 16(2), 241-249 (2016-09-20)
Fragile X syndrome (FXS) is an inherited form of intellectual disability that is usually caused by expansion of a polymorphic CGG repeat in the 5' untranslated region of the X-linked FMR1 gene, which leads to hypermethylation and transcriptional silencing. Two

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