推薦產品
生物源
goat
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
rat, canine, human, mouse
技術
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... SNAP25(6616)
一般說明
Synaptosome associated protein 25 (SNAP25) is a component of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex. It is expressed in pancreatic endocrine cells. The gene encoding this protein is localized on human chromosome 20p12.2.
免疫原
Peptide with sequence C-DEANQRATKMLGSG from the C Terminus of the protein sequence according to NP_003072.2; NP_570824.1.
生化/生理作用
Synaptosome associated protein 25 (SNAP25) has a role in vesicle mobilization, exocytosis and may have a role in fusion of synaptic vesicles. It is involved in modulating the activity of potassium voltage gated (Kv) 2.1 channels. SNAP25 has been associated with attention-deficit/hyperactivity disorder (ADHD).
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
Synaptosome-Associated Protein 25 (SNAP25) Gene Association Analysis Revealed Risk Variants for ASD, in Iranian Population.
Journal of Molecular Neuroscience (2017)
SNAP25 is associated with schizophrenia and major depressive disorder in the Han Chinese population.
The Journal of Clinical Psychiatry (2015)
Detection of lower levels of SNAP25 using multiple microarray systems and its functional significance in medulloblastoma.
International Journal of Molecular Medicine (2017)
Synaptosomal Protein of 25 kDa (Snap25) Polymorphisms Associated with Glycemic Parameters in Type 2 Diabetes Patients.
Journal of Diabetes Research (2016)
Biochemical and biophysical research communications, 447(2), 311-314 (2014-04-10)
Recent reports indicate that interruption of acetylcholine release by intrastriatal injection of botulinum neurotoxin type A (BoNT/A) in a rat Parkinson's disease model reduces pathogenic behavior without adverse side effects such as memory dysfunction. Current knowledge suggests that BoNT/A subtype
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