SAB2500606

Anti-LXR α/LXR β antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• 同義詞: Anti-NR1H3, Anti-RLD-1
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: goat
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 物種活性: human
• 技術: indirect ELISA: suitable; western blot: suitable
• UniProt登錄號: P55055
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... NR1H3; NR1H2(10062)

描述

一般說明

Liver X receptor α and β (LXR-α/LXR-β) are members of LXRs that belong to the nuclear receptor superfamily. LXR-α is expressed predominantly in macrophages, liver, intestine, kidney, lung and adipose tissue. The protein contains a DNA-binding domain that requires the ligand-binding domain to heterodimerize with a retinoid X receptor partner for its DNA-binding activity. The gene encoding this protein is localized on to human chromosome 11p11.2.

免疫原

Peptide with sequence CRLQDKKLPPLLSEI from the internal region of the protein sequence according to NP_005684; NP_009052.

生化／生理作用

Liver X receptor α (LXR-α) has an important role in the control of cholesterol homeostasis. LXRs have been found to regulate inflammatory response in macrophages. They are also involved in the regulation of cell proliferation.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319
• 防範說明: P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2
• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable