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重要文件

SAB2500485

Sigma-Aldrich

Anti-GPX3 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

同義詞:

Anti-Extracellular glutathione peroxidase, Anti-GPx-P, Anti-GSHPx-3, Anti-GSHPx-P, Anti-Glutathione peroxidase 3 (plasma)

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

goat

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

mouse, canine, rat, human

技術

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... GPX3(2878)

一般說明

Glutathione peroxidase 3 (GPX3) belongs to the glutathione peroxidase (GPX) family. It is located on human chromosome 5q23.

免疫原

Peptide with sequence C-NQFGKQEPGENSE from the internal region of the protein sequence according to NP_002075.2.

應用

Anti-GPX3 antibody has been used in western blotting.

生化/生理作用

Glutathione peroxidase 3 (GPX3) blocks oxidative damages by decreasing redundant reactive oxygen species (ROS). It plays a major role in solid tumors and hematological malignancies. GPX3 also plays an important role in the effectiveness of leukemic stem cells (LSCs) and self renewal actions of hematopoietic stem cells (HSCs).

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

Lot/Batch Number

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存取文件庫

GPX3 methylation in bone marrow predicts adverse prognosis and leukemia transformation in myelodysplastic syndrome
J D Zhou, et al.
Cancer Medicine, 6(1), 267-274 (2017)
Relationship between proinflammatory and antioxidant proteins with the severity of cardiovascular disease in type 2 diabetes mellitus
B G Fontana, et al.
International Journal of Molecular Sciences, 16(5), 9469-9483 (2015)
Beatriz García-Fontana et al.
International journal of molecular sciences, 16(5), 9469-9483 (2015-04-30)
Type 2 diabetes mellitus patients are at significant risk of cardiovascular disease, however, the pathophysiology of these complications is complex and incompletely known in this population. The aim of this study was to compare the serum proteome of patients with

Global Trade Item Number

庫存單位GTIN
SAB2500485-100UG4061832484082

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