SAB2108883

Anti-IL1B (N-terminal) antibody produced in rabbit biotin conjugated

affinity isolated antibody

• 分類程式碼代碼: 12352203

屬性

• 生物源: rabbit
• 共軛: biotin conjugate
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: 17 kDa
• 物種活性（以同源性預測）: mouse, human, rabbit, horse, canine
• 濃度: 0.5 mg/mL
• 技術: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 4-8 μg/mL
• NCBI登錄號: NM_000576
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... IL1B(3553)

描述

一般說明

IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. The gene encoding IL1B and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

免疫原

Synthetic peptide directed towards the N terminal region of human IL1B

序列

Synthetic peptide located within the following region: MAEVPELASEMMAYYSGNEDDLFFEADGPKQMKCSFQDLDLCPLDGGIQL

外觀

Supplied at 0.5 mg/ml in phosphate-buffered saline, 0.09% sodium azide

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: nwg
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable