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Key Documents

SAB2101563

Sigma-Aldrich

Anti-NEDD9 antibody produced in rabbit

affinity isolated antibody

同義詞:

Anti-CAS-L, Anti-CASL, Anti-DJ49G10.2, Anti-HEF1, Anti-Neural precursor cell expressed, developmentally down-regulated 9

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

93 kDa

物種活性

guinea pig, rat, rabbit, human, mouse

濃度

0.5 mg - 1 mg/mL

技術

immunohistochemistry: suitable
western blot: suitable

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

human ... NEDD9(4739)

免疫原

Synthetic peptide directed towards the middle region of human NEDD9

生化/生理作用

Variation in NEDD9 is associated wih susceptibility to late-onset Alzheimer and Parkinson diseases. Changes in expression of the scaffold protein HEF1/CAS-L/NEDD9 were found to be a potent prometastatic stimulus in melanoma and other cancers.

序列

Synthetic peptide located within the following region: DLVDGINRLSFSSTGSTRSNMSTSSTSSKESSLSASPAQDKRLFLDPDTA

外觀

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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存取文件庫

Haihui Lu et al.
Nature cell biology, 16(11), 1105-1117 (2014-10-01)
The cell-biological program termed the epithelial-mesenchymal transition (EMT) confers on cancer cells mesenchymal traits and an ability to enter the cancer stem cell (CSC) state. However, the interactions between CSCs and their surrounding microenvironment are poorly understood. Here we show

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