SAB1412648

ANTI-STAU1 antibody produced in mouse

clone 4D6, purified immunoglobulin, buffered aqueous solution

• 同義詞: FLJ25010, STAU, STAU1
• 分類程式碼代碼: 12352203
• NACRES: NA.41
• 共軛: unconjugated
• application: ELISA (i); IF
• 無性繁殖: 4D6, monoclonal
• 物種活性: human
• 技術: indirect ELISA: suitable; indirect immunofluorescence: suitable

屬性

• 生物源: mouse
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: 4D6, monoclonal
• 形狀: buffered aqueous solution
• 分子量: antigen 36.19 kDa
• 物種活性: human
• 技術: indirect ELISA: suitable; indirect immunofluorescence: suitable
• 同型: IgG2bκ
• NCBI登錄號: NM_004602
• UniProt登錄號: O95793
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... STAU1(6780)

描述

一般說明

Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5′UTR. (provided by RefSeq)

免疫原

STAU1 (NP_004593, 401 a.a. ~ 496 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
PHGPLTRPSEQLDYLSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQSTEMPRTGNGPMSVCGRC

外觀

Solution in phosphate buffered saline, pH 7.4

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable