SAB1412627

ANTI-ZIC2 antibody produced in mouse

clone 4A7, purified immunoglobulin, buffered aqueous solution

• 同義詞: HPE5, ZIC2
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: mouse
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: 4A7, monoclonal
• 形狀: buffered aqueous solution
• 分子量: antigen 32.89 kDa
• 物種活性: human
• 技術: indirect ELISA: suitable; western blot: 1-5 μg/mL
• 同型: IgG2aκ
• NCBI登錄號: NM_007129
• UniProt登錄號: O95409
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... ZIC2(7546)

描述

一般說明

This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13. (provided by RefSeq)

免疫原

ZIC2 (NP_009060, 151 a.a. ~ 216 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
SDAQGHLLFP GLPEQHGPHG SQNVLNGQMR LGLPGEVFGR SEQYRQ VASP RTDPY

外觀

Solution in phosphate buffered saline, pH 7.4

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable