SAB1300896

Anti-LECT2 (N-term) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 同義詞: Anti-HLECT2, Anti-LECT2, Anti-Leukocyte cell-derived chemotaxin 2
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 物種活性: human
• 技術: immunohistochemistry: 1:50-1:100; indirect ELISA: 1:1000
• NCBI登錄號: NP_002293
• UniProt登錄號: O14960
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... LECT2(3950)

描述

一般說明

Leukocyte cell-derived chemotaxin 2 (LECT2) is a hepatokine, encoded by the gene mapped to human chromosome 5q31.1–q32. The gene spanning ~8kb of genomic DNA contains four exons and three introns. LECT2 is a secreted protein with a molecular mass of 16kDa. The encoded protein is mainly expressed in vascular, endothelial and smooth muscle cells, adipocytes, cerebral nerve cells, apical squamous epithelia, parathyroid cells, sweat, sebaceous glandular epithelia and Hassall bodies. Additionally, it is also expressed at high levels in fetal and adult liver.

免疫原

LECT2 (NP_002293, 34-68)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human LECT2.

生化／生理作用

Leukocyte cell-derived chemotaxin 2 (LECT2) acts as a chemotactic factor for neutrophils. It is also implicated in the inflammatory response and insulin resistance. Low serum LECT2 level increases the risk of susceptibility to diabetic retinopathy (DR). Overexpression of the gene has been observed in circulating plasma of non-alcoholic fatty liver disease (NAFLD) patients.

外觀

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: nwg
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable