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Merck
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重要文件

S8502

Sigma-Aldrich

(−)-Scopolamine methyl bromide

≥98% (HPLC), powder

同義詞:

Hyoscine methyl bromide, Methscopolamine bromide

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About This Item

經驗公式(希爾表示法):
C18H24NO4 · Br
CAS號碼:
分子量::
398.29
EC號碼:
MDL號碼:
分類程式碼代碼:
12352116
PubChem物質ID:
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

powder

光學活性

[α]25/D −25°, c = 5 in H2O(lit.)

顏色

white

溶解度

H2O: 50 mg/mL

SMILES 字串

[Br-].[H][C@]12C[C@@H](C[C@]([H])([C@@]3([H])O[C@@]13[H])[N+]2(C)C)OC(=O)[C@H](CO)c4ccccc4

InChI

1S/C18H24NO4.BrH/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11;/h3-7,12-17,20H,8-10H2,1-2H3;1H/q+1;/p-1/t12-,13-,14-,15+,16-,17+;/m1./s1

InChI 密鑰

CXYRUNPLKGGUJF-RAFJPFSSSA-M

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應用

(−)-Scopolamine methyl bromide was administered to rats to inhibit the peripheral cholinergic effects induced by pilocarpine.10,11

生化/生理作用

Competitive muscarinic acetylcholine receptor antagonist.
Scopolamine is an anti-muscarinic and cholinolytic alkaloid that inhibits parasympathetic-cholinergic system.7 The central effects include hallucinations, disorientation, restlessness and euphoria.8 Scopolamine disturb the stimulus detection performance in rats by interfering with the reticular cholinergic pathways.9

注意

Shelf-life of the powder is at least five years when stored at room temperature.

象形圖

Exclamation markEnvironment

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Acute 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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