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Key Documents

S4881

Sigma-Aldrich

葡萄球菌肠毒素B 来源于金黄色葡萄球菌

同義詞:

SEB, 肠毒素B,葡萄球菌

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About This Item

CAS號碼:
MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.25

包含

sodium phosphate buffer as balance

品質等級

成份

Protein, ~25% Lowry

存貨情形

not available in USA

雜質

Staphylococcal enterotoxin A (SEA), essentially free

應用

metabolomics
vitamins, nutraceuticals, and natural products

儲存溫度

2-8°C

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應用

与 MHC II 类分子和 T 细胞受体(TCR)的特异性 Vβ 区结合的葡萄球菌肠毒素 B(SEB),可导致单核细胞/巨噬细胞和 T 淋巴细胞的激活,可用作超抗原和免疫系统激活剂。 SEB 可用作 SEB 检测系统开发中的参考材料。

生化/生理作用

T 淋巴细胞的超抗原。 与主要组织相容性复合体(MHC)抗原和 CD28 结合的免疫系统激活剂。

包裝

包装尺寸基于蛋白质含量。

相關產品

產品號碼
描述
訂價

象形圖

Skull and crossbones

訊號詞

Danger

危險分類

Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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存取文件庫

A Herman et al.
Annual review of immunology, 9, 745-772 (1991-01-01)
Superantigens combine with MHC class-II molecules to form the ligands that stimulate T cells via the V beta element of the T-cell receptor. Two groups of superantigens have been described so far: first, endogenous murine products that include the Mls
Bacterial superantigens
Proft, T. and Fraser, J.D.
Clinical and Experimental Immunology, 133, 299-299 (2008)
Katharina Bröker et al.
Journal of translational medicine, 17(1), 6-6 (2019-01-04)
Hepatitis B virus (HBV) infections represent a global health problem and chronic hepatitis B (CHB) leads to liver cirrhosis and hepatocellular carcinoma. Thus, timely diagnosis of hepatitis B is crucial to ensure adequate treatment. We developed a powerful and rapid
Winnie Bergstedt et al.
PloS one, 5(6), e11277-e11277 (2010-07-02)
Tuberculin is still the only available skin test reagent for the diagnosis of mycobacterial infection. The product has a remarkable sensitivity, but poor specificity. Previous studies, including two human phase I clinical trials, have indicated that rdESAT-6 has a potential
Clarifying the mechanism of superantigen toxicity.
John D Fraser
PLoS biology, 9(9), e1001145-e1001145 (2011-09-21)

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