生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
IgG fraction of antiserum
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 35 kDa
物種活性
rat
技術
indirect immunofluorescence: 1:500-1:1000 using of rat kidney NRK cell line
western blot: 1:1000-1:2000 using whole cell extract of rat kidney NRK cell line
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
rat ... Stx7(60466)
一般說明
Syntaxin 7 is a 35kDa protein and is a member of t-Soluble N-ethylmaleimide-sensitive factor activating protein receptor (SNARE) protein family. It is widely expressed in multiple tissues.
免疫原
synthetic peptide corresponding to amino acids 131-149 located at the mid-region of rat syntaxin 7, conjugated to KLH. This sequence is highly conserved (two amino acid substitutions) in mouse and human syntaxin 7 (~80% identity).
應用
Anti-Syntaxin 7 antibody produced in rabbit has been used in immunoblotting and immunofluorescence.
生化／生理作用
Syntaxin 7, localized on membrane compartments of late endosomes, facilitates fusion of late endosomes with lysosomes. The protein also helps in lysosomal biogenesis. Mutant syntaxin 7 lacking the transmembrane domain blocks endocytic transport from the early to late endosome. Syntaxin 7 has been described to play an important role during phagocytosis.
外觀
0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Syntaxin 7 mediates endocytic trafficking to late endosomes
Nakamura N, et al.
The Journal of Biological Chemistry, 275(9), 6523-6529 (2000)
Differential roles of syntaxin 7 and syntaxin 8 in endosomal trafficking
Prekeris R, et al.
Molecular Biology of the Cell, 10(11), 3891-3908 (1999)
Syntaxins 13 and 7 function at distinct steps during phagocytosis
Collins RF, et al.
Journal of Immunology, 169(6), 3250-3256 (2002)
Richard F Collins et al.
Journal of immunology (Baltimore, Md. : 1950), 169(6), 3250-3256 (2002-09-10)
The phagosome is a dynamic organelle that undergoes progressive changes to acquire the machinery required to kill and degrade internalized foreign particles. This maturation process involves sequential interaction of newly formed phagosomes with several components of the endocytic pathway. The
N Nakamura et al.
The Journal of biological chemistry, 275(9), 6523-6529 (2000-02-29)
The lysosome functions are ensured by accurate membrane trafficking in the cell. We found that mouse syntaxin 7 could complement yeast vam3 and pep12 mutants defective in docking/fusion to vacuolar and prevacuolar membranes, respectively. Immunohistochemical studies showed that syntaxin 7
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