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Merck
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重要文件

S3386

Sigma-Aldrich

山梨糖醇酐倍半油酸酯

nonionic surfactant

同義詞:

Arlacel® 83, Span® 83

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About This Item

CAS號碼:
EC號碼:
MDL號碼:
分類程式碼代碼:
12352211
PubChem物質ID:
NACRES:
NA.25

生物源

corn

品質等級

蒸汽壓力

0.81 psi ( 20 °C)

形狀

liquid

折射率

n20/D 1.478 (lit.)

密度

0.989 g/mL at 25 °C (lit.)

官能基

ester

脂質類型

oils

運輸包裝

ambient

儲存溫度

room temp

SMILES 字串

OC[C@@H](O)C1OC[C@H](O)[C@H]1O.OC[C@@H](O)C2OC[C@H](O)[C@H]2O.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O

InChI

1S/3C18H34O2.2C6H12O5/c3*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;2*7-1-3(8)6-5(10)4(9)2-11-6/h3*9-10H,2-8,11-17H2,1H3,(H,19,20);2*3-10H,1-2H2/b3*10-9-;;/t;;;2*3-,4+,5-,6-/m...11/s1

InChI 密鑰

SPFRYHCSFBFNTR-RKGWDQTMSA-N

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一般說明

倍半油酸山梨坦(SSO) 是一种山梨醇衍生物乳化剂。它是外用皮质类固醇、外用抗生素、外用抗真菌剂、保湿霜和乳液以及外用维A酸中的常见乳化剂成分。

生化/生理作用

倍半油酸山梨坦在生产球形丙烯酰胺微珠的聚合过程中可用作稳定剂。它已被用于许多外用药物。 最近发现SSO与过敏性皮炎有关。

其他說明

脂肪酸组成:油酸(C18:1)约70%;主要用于平衡的棕榈酸(C16:0)、硬脂酸(C18:0)和亚油酸(C18:2)。

法律資訊

Arlacel is a registered trademark of Croda International PLC
Span is a registered trademark of Croda International PLC

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

235.4 °F - closed cup

閃點(°C)

113 °C - closed cup

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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分析證明 (COA)

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Contact dermatitis.
Flora B de Waard-van der Spek et al.
Contact dermatitis, 59(1), 67-67 (2008-07-05)
E Larmi et al.
Contact dermatitis, 19(5), 368-371 (1988-11-01)
In order to study the effects of an emulsifier on non-immunologic immediate contact reactions, 500, 250, 125, 62, and 31 mM benzoic acid (BA) was tested in 12 medical students on a skin area of the upper back treated with
M Iwata et al.
Journal of microencapsulation, 16(1), 49-58 (1999-02-11)
PLGA multiphase microspheres were prepared by the multiple emulsion solvent evaporation method using acetonitrile as the polymer solvent and mineral oil as the evaporation medium. The preparation process was further developed in the present study to reduce the particle size
Kinetic evaluation of biotransformation of benzaldehyde to L-phenylacetylcarbinol by immobilized pyruvate decarboxylase from Candida utilis
Shin HS and Rogers PL
Biotechnology and Bioengineering, 49(4), 429-436 (1996)
Adam Asarch et al.
Dermatitis : contact, atopic, occupational, drug, 19(6), 339-341 (2009-01-13)
Sorbitol-based emulsifiers such as sorbitan sesquioleate (SSO) are commonly used in topical corticosteroids, topical antibiotics, topical antifungals, moisturizing creams and lotions, and topical retinoids. Contact dermatitis from sorbitol derivatives appears to be increasingly prevalent. Patch-testing with SSO can be useful

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