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Merck
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重要文件

S0127

Sigma-Aldrich

磺胺噻唑 钠盐

≥99%

同義詞:

4-氨基-N-(2-噻唑基)苯磺酰胺 钠盐

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About This Item

經驗公式(希爾表示法):
C9H8N3NaO2S2
CAS號碼:
分子量::
277.30
Beilstein:
3802297
EC號碼:
MDL號碼:
分類程式碼代碼:
51283955
PubChem物質ID:
NACRES:
NA.85

生物源

synthetic (Organic)

化驗

≥99%

形狀

powder

顏色

white to off-white

溶解度

H2O: soluble 50 mg/mL

抗生素活性譜

Gram-negative bacteria
Gram-positive bacteria
mycoplasma

作用方式

DNA synthesis | interferes
enzyme | inhibits

SMILES 字串

Nc1ccc(cc1)S(=O)(=O)N([Na])c2nccs2

InChI

1S/C9H8N3O2S2.Na/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9;/h1-6H,10H2;/q-1;+1

InChI 密鑰

GWIJGCIVKLITQK-UHFFFAOYSA-N

尋找類似的產品? 前往 產品比較指南

一般說明

化学结构:磺胺

應用

磺胺噻唑是一种短效磺胺药。在发现毒性较低的替代品之前,它是一种常见的口服和外用抗生素。它不再用于人类。在实验动物的饮食中加入磺胺噻唑可抑制肠道细菌形成叶酸。这确保了动物可用叶酸的唯一来源是它们的饮食

生化/生理作用

磺胺噻唑是一种磺胺类抗生素,通过抑制二氢丙酸合成酶来阻断二氢叶酸的合成。磺胺噻唑是细菌对氨基苯甲酸(PABA)的竞争性抑制剂,它是细菌合成叶酸所必需的。它对革兰氏阳性细菌、革兰氏阴性细菌和衣原体均具有抗性。抗性产生机制是通过改变二氢蝶酸合成酶或叶酸合成的替代途径。

其他說明

保存于密闭容器内,置于干燥通风处。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

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