推薦產品
物種活性
human
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
輸入
sample type plasma
sample type cell culture supernatant(s)
sample type serum sample(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 24 pg/ml
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... ECM1(1893)
一般說明
Extracellular matrix protein 1 (ECM1) is a glycoprotein. It is expressed in skin and other tissues. The gene encoding this protein is localized on human chromosome 1q21.2.
This ELISA antibody pair detects Human Extracellular Matrix Protein 1 (ECM1)
應用
For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.
Please refer to the attached Protocolfor details.
生化／生理作用
Extracellular matrix protein 1 (ECM1) has a role in cell proliferation, mineralization and angiogenesis. The protein has been shown to have a role in cancer invasion and progression. It is associated with hepatocellular carcinoma. Mutations in the ECM1 gene have been linked to lipoid proteinosis. The protein also promotes the Warburg effect, which is an oncogenic switch that allows cancerous cells to take in more glucose than non-cancerous cells.
其他說明
A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8A - Combustible corrosive hazardous materials
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
CD5L is a pleiotropic player in liver fibrosis controlling damage, fibrosis and immune cell content.
Cristina Bárcena et al.
EBioMedicine, 43, 513-524 (2019-05-12)
Chronic hepatic inflammation leads to liver fibrosis, which may progress to cirrhosis, a condition with high morbidity. Our aim was to assess the as yet unknown role of innate immunity protein CD5L in liver fibrosis. CD5L was measured by ELISA
ECM1 promotes migration and invasion of hepatocellular carcinoma by inducing epithelial-mesenchymal transition
Chen H, et al.
World Journal of Surgical Oncology, 14(1), 195-195 (2016)
Danielle E Baranova et al.
PloS one, 13(1), e0190026-e0190026 (2018-01-03)
Vibrio cholerae O1 is one of two serogroups responsible for epidemic cholera, a severe watery diarrhea that occurs after the bacterium colonizes the human small intestine and secretes a potent ADP-ribosylating toxin. Immunity to cholera is associated with intestinal anti-lipopolysaccharide
Alee Choi et al.
International journal of molecular sciences, 21(17) (2020-09-03)
Extracellular matrix (ECM) components play an important role in maintaining skeletal muscle function, but excessive accumulation of ECM components interferes with skeletal muscle regeneration after injury, eventually inducing fibrosis. Increased oxidative stress level caused by dystrophin deficiency is a key
Hege Kampen Pihlstrøm et al.
PloS one, 15(12), e0243759-e0243759 (2020-12-17)
Following a successful renal transplantation circulating markers of inflammation may remain elevated, and systemic inflammation is associated with worse clinical outcome in renal transplant recipients (RTRs). Vitamin D-receptor (VDR) activation is postulated to modulate inflammation and endothelial function. We aimed
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
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