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Key Documents

RAB0820

Sigma-Aldrich

小鼠Lepr / Leptin受体ELISA试剂盒

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About This Item

分類程式碼代碼:
41116158
NACRES:
NA.32

物種活性

mouse

包裝

kit of 96 wells (12 strips x 8 wells)

技術

ELISA: suitable

輸入

sample type cell culture supernatant(s)
sample type serum
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 32 pg/mL
standard curve range: 32.77-8000 pg/mL

檢測方法

colorimetric

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

mouse ... Lepr(16847)

一般說明

The antibody pair provided in this kit recognizes mouse Leptin Receptor.

應用

请参考Protocol了解详情。

生化/生理作用

Leptin receptor (Lepr) belonging to class I cytokine receptor family, binds with leptin, a small non-glycosylated peptide hormone and transduces signal. Lepr expression is present in brain and immune cells. Signal transduction through Lepr regulates fat metabolism in mammals. Lepr is part of the hematopoietic pathway. Lepr is a marker for mesenchymal stem/stromal cells (MSCs) and regulates the regenerative process of bone and cartilage after injury. Lepr regulates pancreatic β cell functions. Polymorphism in Lepr causes metabolic diseases like obesity, dyslipidemia, hypertension and Type 2 diabetes. Mutations in Lepr associates with polycystic ovarian syndrome (PCOS) susceptibility.

套裝中的組件也可單獨購買

產品號碼
描述
SDS

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS

  • RABSTOP3ELISA Stop Solution (Item I)SDS

  • RABWASH420X Wash Buffer (Item B)SDS

象形圖

Corrosion

訊號詞

Warning

危險聲明

防範說明

危險分類

Met. Corr. 1

儲存類別代碼

8A - Combustible, corrosive hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

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您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

A role for leptin and its cognate receptor in hematopoiesis
Bennett BD, et al.
Current Biology, 6(9), 1170-1180 (1996)
Leptin and leptin receptors in salivary glands of primary Sjogren?s syndrome
Erbasan F, et al.
Pathology Research and Practice, 212(11), 1010-1014 (2016)
LEPR gene polymorphism and plasma soluble leptin receptor levels are associated with polycystic ovary syndrome in Han Chinese women
Tu X, et al.
Personalized Medicine, 14(4), 299-307 (2017)
Plasma soluble leptin receptor levels are associated with pancreatic beta-cell dysfunction in patients with type 2 diabetes
Morioka T, et al.
Journal of diabetes investigation, 9(1), 55-62 (2018)
Leptin receptor makes its mark on MSCs
Matsuzaki Y, et al.
Cell Stem Cell, 15(2), 112-114 (2014)

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