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Key Documents

RAB0365

Sigma-Aldrich

人类 MMP-2 ELISA 试剂盒

for serum, plasma, cell culture supernatant

同義詞:

MMP-2, Matrix metalloproteinase-2

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About This Item

分類程式碼代碼:
41116158
NACRES:
NA.32

物種活性

human

包裝

kit of 96 wells (12 strips x 8 wells)

技術

ELISA: suitable
capture ELISA: suitable

輸入

sample type cell culture supernatant(s)
sample type plasma
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 3,500 pg/mL
standard curve range: 3.3-800 ng/mL

檢測方法

colorimetric

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

human ... MMP2(4313)

一般說明

The Human MMP-2 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human MMP-2 in serum, plasma, cell culture supernatants and urine.

免疫原

Recombinant Human MMP2

應用

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human MMP-2 ELISA kit has been used for the determination of MMP-2 in serum samples and cell supernatant.
Human MMP-2 ELISA Kit has been used in ELISA (enzyme-linked immunosorbent assay).

生化/生理作用

Matrix metalloproteinases (MMPs) enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, which has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. High levels of MMP-2 are observed in the acute phase of transverse myelitis. It is upregulated in colorectal carcinoma and is associated with poor survival outcome. MMP-2 gene haplotypes are also linked with risk of thoracic aortic dissection, a cardiovascular disorder with high death rate.

其他說明

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

套裝中的組件也可單獨購買

產品號碼
描述
SDS

  • RABELADEELISA 5X Assay/Sample Diluent Buffer E (Item E2)SDS

  • RABSTOP3ELISA Stop Solution (Item I)SDS

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS

  • RABWASH420X Wash Buffer (Item B)SDS

象形圖

Corrosion

訊號詞

Warning

危險聲明

防範說明

危險分類

Met. Corr. 1

儲存類別代碼

8B - Non-combustible corrosive hazardous materials

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

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Increased expression of 72-kd type IV collagenase (MMP-2) in human aortic atherosclerotic lesions.
Li Z, et. al.
The American Journal of Pathology, 148, 121-128 (1996)
IL-33 enhances glioma cell migration and invasion by upregulation of MMP2 and MMP9 via the ST2-NF-kappaB pathway
Zhang J F, et al.
Oncology Reports, 38(4), 2033-2042 (2017)
IL-33 enhances glioma cell migration and invasion by upregulation of MMP2 and MMP9 via the ST2-NF-?B pathway.
Zhang JF
Oncology Reports, 38, 2033-2033 (2017)
Matrix metalloproteinases: role in skeletal development and growth plate disorders.
Malemud CJ
Frontiers in Bioscience, 11, 1702-1715 (2006)
Active matrix metalloprotease-9 is associated with the collagen capsule surrounding the Madurella mycetomatis grain in mycetoma.
Geneugelijk K
PLoS Neglected Tropical Diseases, 8, e2754-e2754 (2014)

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